Position/Title: Formulation Development, Senior Research Scientist
- Description
As part of a dynamic multi-disciplinary pharmaceutical development team, you will be responsible for developing formulations for pulmonary delivery with optimal performance characteristics including delivery, biocompatibility, bioavailability and stability. The candidate will lead the formulation development and optimization effort for optimal liquid pulmonary delivery. Responsibilities will include assessment of formulation suitability for aerosol delivery, formulation characterizations and optimization, formulation stability and material compatibility and data analysis. Other responsibility includes assisting in integration of process into production of clinical trial materials and eventually commercial deliverables. The candidate will work closely with aerosol technology group for formulation optimization, characterization team and particle/process engineers to create suitable particles and to scale the product to commercial scale and assist with technology transfer to the commercial group. In addition, you will be expected to write technical reports and deliver technical presentations to senior management and project teams. - Qualifications
- Education: Ph.D. in Pharmaceutical Chemistry, Chemistry, Biochemistry, Chemical Engineering, or related discipline with a proven track record within pulmonary formulation development and chemistry.
- Experience: 5-8 years experience of pharmaceutical or biotechnology industrial experience developing formulization for biomolecules with optimal delivery and stability properties.
- Required knowledge and skill:
- In depth knowledge in small and large molecules formulations, selection of excipients (e.g. stability enhancer, permeability enhancer, bioadhesion, tonicity enhancer), selection of propellant, etc., including thorough understanding of the possible chemistry.
- Experiences with discovery and development of formulation for non-invasive delivery (particularly pulmonary).
- Familiar with different formulation and aerosol characterizations, such as viscometer, DSC, surface tensiometer, SEM, NGI, ACI, etc. and understand the concept of different instruments.
- Familiarity with aerosol characterizations.
- Profound literature and IP search and review skills.
- Capable of designing stability study based on ICH guideline.
- Possess a broad expertise, a strong work ethic and excellent oral and written communication skills.
- Capable of functioning at a high level, independently and within a cross-functional team environment, whilst maintaining clear communication with the group.
- Possess strong trouble-shooting and problem solving skills and be able to work quickly and accurately in a demanding, fast paced work environment.
- Proven track record of creativity and problem solving.
- Strong presentation skills and scientific/technical writing skills.
- Job Complexity
- Demonstrated success in technical proficiency, scientific creativity, collaboration with others and independent thought.
- Works on complex problems in which analysis of situations or data requires an in-depth evaluation of various factors.
- Exercises judgement within broadly defined practices and policies in selecting methods, techniques and evaluation criteria for obtaining results.
Send resume to:
Career OpportunitiesMAP Pharmaceuticals, Inc.
2400 Bayshore Parkway, Suite 200
Mountain View, CA 94043 Or e-mail resume to: [ back to careers ]