Science & Technology

Innovative Delivery

We not only develop novel forms of proven drugs—we also innovate the delivery systems used to optimize the administration of these drugs.

TEMPO® Inhaler Platform

We designed our proprietary TEMPO® inhaler to enable accurate and reproducible pulmonary delivery of the drug particles we develop. Our TEMPO inhaler is an innovative, next-generation metered dose inhaler (MDI). The TEMPO inhaler incorporates the size, ease of use and convenience advantages associated with standard MDIs, and is designed to overcome their greatest limitations: inconsistent dosing, drug delivery inefficiency and the need for patients to synchronize a breath with manual triggering of the device, which is particularly difficult for certain patient populations such as children and elderly patients.

The TEMPO inhaler is designed to offer the following attributes:

  • Automatic release of therapy: Our triggering technology is tuned for each particular drug so that drug release is synchronized to a specified point in the breathing cycle to allow the released drug to reach the targeted area of the respiratory tract.
  • Plume speed control: Our TEMPO inhaler controls and slows down the drug plume to match the speed of the patient’s inhaled breath, so that more of the drug is entrained in the inhaled air and carried into the lungs.
  • Reliable dosing: The TEMPO inhaler also includes a dose counter to display how many doses remain available for use, so that patients can track their medication use and remaining supply. The dose counter can prevent dispensing of additional doses after a maximum number of doses have been delivered.
  • Convenient, multiple-dose use: The TEMPO inhaler does not use electronics or batteries and can conveniently contain multiple doses. It can include up to a month’s supply depending on the drug, in a small, handheld inhaler approximately the same size as a conventional MDI and it may be used with small molecule drugs and biologics.

 Our proprietary TEMPO® inhaler designed for ease of use and consistent dosing